Abstract | INTRODUCTION: AREAS COVERED: We undertook a literature review to identify English language, national and international clinical guidelines for NAFLD regarding diagnosis, assessment and management, and determined their points of agreement and difference. Additionally, we investigated published literature relating to real-world management of NAFLD and NASH. EXPERT OPINION: National (China, England/Wales, Italy, the USA) and international society (Asia-Pacific, Europe, World Gastroenterology Organization) guidelines were identified and analyzed. All guidelines addressed identifying and diagnosing subjects with likely NAFLD, as well as assessment and management of individuals with risk factors for advanced disease, including fibrosis. Real-world practice reveals widespread suboptimal awareness and implementation of guidelines. In the absence of proven therapeutics, such gaps risk failure to recognize patients in need of specialist care and monitoring, highlighting the need for clear, easy-to-apply care pathways to aid in reducing the clinical and humanistic burden of NAFLD and NASH.
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Authors | Jörn M Schattenberg, Quentin M Anstee, Cyrielle Caussy, Elisabetta Bugianesi, Branko Popovic |
Journal | Expert review of gastroenterology & hepatology
(Expert Rev Gastroenterol Hepatol)
Vol. 15
Issue 11
Pg. 1253-1266
(Nov 2021)
ISSN: 1747-4132 [Electronic] England |
PMID | 34493137
(Publication Type: Journal Article, Review, Video-Audio Media)
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Topics |
- Diagnosis, Differential
- Humans
- Mass Screening
- Non-alcoholic Fatty Liver Disease
(diagnosis, therapy)
- Practice Guidelines as Topic
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