The diagnostic and prognostic value of tumor markers in giant mediastinal endodermal sinus tumor with prolonged survival: Twelve-year follow up after radical resection.

Abstract

We report a case of 16 -year male who presented with nonproductive cough, chest pain, and hemoptysis. His chest -x-ray and computerized tomographic scan (CT) of the thorax with contrast enhancement revealed a large mediastinal mass mostly occupying the left hemithorax. Percutaneous CT scan-guided biopsy of the mediastinal mass was reported as an endodermal sinus tumor (EDST). Serum alpha-fetoprotein levels were markedly raised (120,000 ng/ml). After completion of chemotherapy repeat, CT scan of the thorax revealed a large residual mass. Radical resection of the tumor was carried out. Twelve-year post-surgical resection follow-up with serial serum alpha-fetoprotein (AFP) tumor marker levels and CT scan of the thorax showed no recurrence.

• Authors: Abdullah M Al Ghamdi, Othman M Al Fraih, Meenal A Al Abdulhai, Ahmed Alshaer, Yousif Al Qahtani, Natasha T Khan, Ikram Ul Haq Chaudhry
• Journal: Annals of medicine and surgery (2012) (Ann Med Surg (Lond)) Vol. 69 Pg. 102744 (Sep 2021) ISSN: 2049-0801 [Print] England
• PMID: 34484723 (Publication Type: Case Reports)
• Copyright: © 2021 The Authors. Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd.