[What is the role of allergen immunotherapy in IgE-mediated food allergy?]

Abstract

In food allergy, allergen avoidance and emergency treatment are still therapeutic hallmarks but, recently, allergen immunotherapy (AIT), with different application routes, has gained more attention. In primary food allergy, oral immunotherapy has been frequently used in clinical trials. This year, an oral immunotherapy preparation for treatment of peanut allergy was licensed in Europe. In secondary food allergy, sublingual and subcutaneous extracts have been used in clinical trials, mostly with cross-reactive pollen allergens. As there is no AIT preparation licensed for this indication, therapy should only be started when there also is a need for treating associated respiratory symptoms.

• Authors: Regina Treudler, Jan-Christoph Simon
• Journal: Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete (Hautarzt) Vol. 72 Issue 9 Pg. 770-775 (Sep 2021) ISSN: 1432-1173 [Electronic] Germany
• Vernacular Title: Welche Rolle spielt die Allergenimmuntherapie bei Immunglobulin-E-vermittelter Nahrungsmittelallergie?
• PMID: 34402920 (Publication Type: Journal Article, Review)
• Copyright: © 2021. Springer Medizin Verlag GmbH, ein Teil von Springer Nature.

Chemical References

• Allergens
• Immunoglobulin E

Topics

• Allergens
• Cross Reactions
• Desensitization, Immunologic
• Food Hypersensitivity (therapy)
• Humans
• Immunoglobulin E
• Sublingual Immunotherapy