Abstract | RATIONALE: PATIENT CONCERNS: INTERVENTIONS: A total of 55 patients with liver cirrhosis and portal hypertension received TIPS treatment from December 2014 to April 2018 were enrolled. Clinical data, including portal pressure, Child-Pugh score, and relevant complications were recorded. OUTCOMES:
TIPS was successfully performed in 54 patients. The overall technical success rate was 98.19% without serious technical complications. After TIPS treatment, portal pressure was significantly reduced from 38.13 ± 4.00 cmH2O to 24.14 ± 3.84 cmH2O (P < 0.05). In addition, symptoms including gastrointestinal bleeding and ascites were improved after TIPS treatment. During the 6 to 21-month follow up, hepatic encephalopathy in 15 patients (27.8%), shunt dysfunction in 5 patients (9.3%), rebleeding in 12 patients (22.2%) and deterioration of liver function in 2 patients (3.7%) were recorded. Moreover, there were no significant differences in the rates of rebleeding and hepatic encephalopathy between patients with PVT and the non-PVT group, whereas the occurrence rate of TIPS dysfunction was higher in the PVT group, but not statistically significant. LESSONS:
TIPS treatment could alleviate the symptoms of liver cirrhosis and portal hypertension in individuals with or without PVT. However, complications during follow-up should be appropriately noted and addressed with corresponding treatments.
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Authors | Dan Zheng, Jiao Yu, Hui Li, Hongying Gan, Jun Wang, Ting Jiang, Huanping Ren, Fan Wu |
Journal | Medicine
(Medicine (Baltimore))
Vol. 100
Issue 27
Pg. e26610
(07 09 2021)
ISSN: 1536-5964 [Electronic] United States |
PMID | 34232216
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc. |
Topics |
- Adult
- Aged
- Female
- Follow-Up Studies
- Humans
- Hypertension, Portal
(etiology, physiopathology, surgery)
- Liver Cirrhosis
(complications)
- Male
- Middle Aged
- Portal Pressure
(physiology)
- Portal Vein
(surgery)
- Portasystemic Shunt, Transjugular Intrahepatic
(methods)
- Retrospective Studies
- Treatment Outcome
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