Application of molecular probes in nuclear imaging of neuroendocrine tumors.

Abstract

Neuroendocrine tumors are a type of heterogeneous tumors originating from neuroendocrine cells derived from the neural crest，which can secrete a variety of amines and peptide hormones.Based on different molecular biomarkers，histologic types and differentiation degrees，individualized nuclear imaging can provide information for the early diagnosis，clinical staging，treatment guidance，and detection of the recurrence and metastasis of neuroendocrine tumor. In this paper，we review the development and application of nuclear medicine molecular imaging probes such as glucose analogs，somatostatin analogues，amine precursors，hormone analogs and enzyme inhibitors in the diagnosis and treatment of neuroendocrine tumors.

• Authors: Jing Yan, Tingting Zhang, Kui Zhao
• Journal: Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences (Zhejiang Da Xue Xue Bao Yi Xue Ban) Vol. 50 Issue 1 Pg. 131-137 (Feb 25 2021) ISSN: 1008-9292 [Print] China
• PMID: 34117850 (Publication Type: Journal Article, Review)

Chemical References

• Molecular Probes

Topics

• Diagnostic Imaging
• Humans
• Molecular Probes
• Neoplasm Recurrence, Local
• Neuroendocrine Tumors (diagnostic imaging)
• Radionuclide Imaging