Abstract |
Meningiomas are the most common primary intracranial tumors. The majority of meningiomas are benign, but they can present different grades of dedifferentiation from grade I to grade III (anaplastic/malignant) that are associated with different outcomes. Radiological surveillance is a valid option for low-grade asymptomatic meningiomas. In other cases, the treatment is usually surgical, aimed at achieving a complete resection. The use of adjuvant radiotherapy is the gold standard for grade III, is debated for grade II and is not generally indicated for radically resected grade I meningiomas. The use of systemic treatments is not standardized. Here we report a review of the literature on the clinical, radiological and molecular characteristics of meningiomas, available treatment strategies and ongoing clinical trials.
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Authors | Ilaria Maggio, Enrico Franceschi, Alicia Tosoni, Vincenzo Di Nunno, Lidia Gatto, Raffaele Lodi, Alba A Brandes |
Journal | CNS oncology
(CNS Oncol)
Vol. 10
Issue 2
Pg. CNS72
(06 01 2021)
ISSN: 2045-0915 [Electronic] England |
PMID | 34015955
(Publication Type: Journal Article, Review)
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Topics |
- Brain Neoplasms
- Child
- Humans
- Meningeal Neoplasms
(diagnostic imaging, therapy)
- Meningioma
(diagnostic imaging, therapy)
- Radiotherapy, Adjuvant
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