Testosterone's Role in COVID-19.

Abstract

COVID-19 consistently displays a higher mortality in males. This sex-specific difference in outcomes is seen not only in the current COVID-19 pandemic, but also in prior viral epidemics and pandemics. Sex hormones, such as testosterone, play a clear role in modulating the immune response, providing a clue that may illuminate the underpinnings of these outcomes. Developing a deeper understanding of these epidemiological findings permits a more effective response to the disease. This article summarizes the sex-specific COVID-19 outcomes, the role of androgens in generating these outcomes, and the potential role of modifying testosterone levels as a form of treatment of COVID-19. Auerbach JM, Khera M. Testosterone's Role in COVID-19. J Sex Med 2021;18:843-848.

• Authors: Jeremy M Auerbach, Mohit Khera
• Journal: The journal of sexual medicine (J Sex Med) Vol. 18 Issue 5 Pg. 843-848 (05 2021) ISSN: 1743-6109 [Electronic] Netherlands
• PMID: 33903045 (Publication Type: Journal Article)
• Copyright: Copyright © 2021. Published by Elsevier Inc.

Chemical References

• Androgens
• Testosterone

Topics

• Androgens
• COVID-19
• Female
• Humans
• Male
• Pandemics
• SARS-CoV-2
• Testosterone