To investigate the impact of different types of
binocular integrated visual field defects on the quality of life in
glaucoma.Ninety-six patients with primary
glaucoma were divided into 5 groups with 25, 24, 11, 15, and 21 patients according to types of the
binocular integrated visual field (BVF) defects. The criteria for BVF grouping included mild visual field defect in
binocular eyes, mild visual field defect in 1 eye and moderate or advanced defect in the other, moderate and non-overlapping visual field defect in both eyes, overlapping and moderate visual field defect in
binocular eyes, and severe defect in both eyes, respectively. The visual field (VF) evaluation was based on H-P-A visual field grading system. Visual acuity, visual field tests and
Glaucoma Quality of Life-15 Questionnaire (GQL-15) were performed for enrolled patients, and
binocular visual field results were integrated. The changes and correlations of the Visual field index values and quality of life scores were compared among the 5 groups. The main factors affecting the quality of life in
glaucoma were analyzed by multiple regression analysis.The best
binocular integrated visual field index (BVFI) and optimal quality of life were observed in group A. The BVFI of group B was better than that of group C or group D, but the peripheral vision glare and dark adaptation were worse. No significant difference was noted between group C and group D in terms of BVFI. However, the glare and dark adaptation in group C were better than that in group D. The BVFI was the lowest and the quality of life was the worst in group E. In all, BVFI and decibels (dB) values were negatively correlated with GQL-15 scores and positively correlated with patients' quality of life.Binocular integrated visual field accurately reflects the visual function in
glaucoma. Higher
binocular integrated visual field indices represent a better quality of life for patients with
glaucoma. Mild to moderate synchronous or complementary
binocular VF defects had a slight effect on the quality of life, while severe and non-compensated VF loss significantly impacts on quality of life in
glaucoma patients.