Sarcoidosis is a multisystemic granulomatous disease. It is rarely isolated in the spleen. The present report describes a case of isolated splenic
sarcoidosis that was diagnosed histologically following laparoscopic
splenectomy. A 76-year-old woman, who underwent radical
nephroureterectomy 7 years earlier for left renal
pelvic cancer and
mastectomy 6 years earlier for left
breast cancer in another facility, was referred to our hospital for assessment of splenic
tumors that were identified during a follow-up examination. The computed tomography scans revealed multiple nodules in the spleen, which had increased in size over 2 years. Positron emission tomography revealed accumulation of [
18F]-fluorodeoxyglucose in the spleen. Laparoscopic
splenectomy was performed and the diagnosis of
sarcoidosis was confirmed histologically. A review of previous reports and the present case suggested that diagnosis of splenic
sarcoidosis should be considered when the CT scans show multinodular splenic
tumors, and
sarcoidosis might be associated with malignant
tumors.