Epitope masking may limit antibody boosting to malaria vaccines.

Abstract

We discuss the study by McNamara et al., who report that low levels of antigen-specific antibodies in serum can limit the boosting of antibody and B-cell responses following immunization with live attenuated malaria sporozoites.

• Authors: Liriye Kurtovic, Michelle J Boyle, James G Beeson
• Journal: Immunology and cell biology (Immunol Cell Biol) Vol. 99 Issue 2 Pg. 126-129 (02 2021) ISSN: 1440-1711 [Electronic] United States
• PMID: 33152796 (Publication Type: Journal Article, Comment)
• Copyright: © 2020 Australian and New Zealand Society for Immunology, Inc.

Chemical References

• Antibodies, Protozoan
• Epitopes
• Malaria Vaccines

Topics

• Animals
• Antibodies, Protozoan
• Epitopes
• Malaria (prevention & control)
• Malaria Vaccines
• Sporozoites (immunology)