[Treatment of stomach ulcer with the Bulgarian preparation Farmaxolon].

Abstract

Thirty-four patients with gastric ulcer were treated with the new Bulgarian preparation pharmaxolon-Pharmachim, for 20 days under clinical conditions. A favourable effect on the clinical symptoms by the pharmaxolon treatment was established but the differences with the control placebo group were statistically insignificant. A total of 47.1% from the gastric ulcers were healed after 20-day treatment and in 32.3% were reduced in size but here the difference from the control placebo group was insignificant. Pharmaxolon, with its therapeutic effect equals the related foreign (Biogastrone, Ultranyl, Caved-S) and Bulgarian preparations (Alcid-V), hence it is recommended for the practice. Elevated transitory arterial pressure was observed in 41% of pharmaxolon-treated patients, not necessitating the discontinuation of the treatment. That requires a periodic control of the arterial pressure of the patients, treated with that new Bulgarian preparation.

• Authors: Kh Brailski, B Dimitrov, V Matov, B Damianov
• Journal: Vutreshni bolesti (Vutr Boles) Vol. 26 Issue 3 Pg. 43-50 ( 1987) ISSN: 0506-2772 [Print] Bulgaria
• Vernacular Title: Lechenie na stomashnata iazva s bulgarskiia preparat Farmaksolon.
• PMID: 3303693 (Publication Type: Clinical Trial, Controlled Clinical Trial, Journal Article)

Chemical References

• Sialic Acids
• Pentagastrin
• N-Acetylneuraminic Acid
• Carbenoxolone
• Glycyrrhetinic Acid

Topics

• Carbenoxolone (therapeutic use)
• Clinical Trials as Topic
• Gastric Acid (metabolism)
• Glycyrrhetinic Acid (analogs & derivatives)
• Humans
• N-Acetylneuraminic Acid
• Pentagastrin
• Sialic Acids (analysis)
• Stomach Ulcer (drug therapy, metabolism)