Impact of intraocular lens characteristics on intraocular lens dislocation after cataract surgery.

Abstract

BACKGROUND:

To assess the influence of intraocular lens (IOL) characteristics on IOL dislocations after cataract surgery.

METHODS:

Patients who underwent cataract surgery at the Department of Ophthalmology Graz, Austria, between 1996 and 2017 were included and medical records were reviewed. Cox proportional-hazard regression models were used to assess the influence of IOL characteristics on IOL dislocation.

RESULTS:

From 68 199 eyes out of 46 632 patients (60.2% women, mean age: 73.71 SD±10.82 years), 111 (0.16%) had an in-the-bag (ITB) disloaction and 35 (0.05%) had an out-of-the-bag (OTB) dislocation. The HRs adjusted for predisposing factors significantly associated with a higher risk for an ITB dislocation were 2.35 (95% CI, 1.45 to 3.8) for hydrophilic IOLs, 2.01 for quadripode IOLs (95% CI, 1.04 to 3.86) and 1.61 (95% CI, 1.04 to 2.48) for haptic angulation. A lower risk was observed for three-piece IOLs (HR=0.58, 95% CI, 0.34 to 0.98) and larger overall IOL diameter (HR=0.79, 95% CI, 0.66 to 0.95). For an OTB dislocation, the HR associated with a higher risk was 18.81 (95% CI, 5.84 to 60.58) for silicone IOLs and 2.12 (95% CI, 0.62 to 7.29) for hydrophilic IOLs. Larger overall IOL diameter (HR 0.40, 95% CI; 0.25 to 0.63) showed a lower risk.

CONCLUSION:

Hydrophilic IOLs, quadripode IOLs and haptic angulation were associated with a higher risk for an ITB dislocation, whereas three-piece IOLs and a larger overall diameter were associated with a lower risk. Risk factors for OTB dislocation were silicone IOLs, hydrophilic IOLs and a smaller overall IOL diameter.

• Authors: Christoph Fidel Mayer-Xanthaki, Gudrun Pregartner, Nino Hirnschall, Thomas Falb, Michael Sommer, Oliver Findl, Andreas Wedrich
• Journal: The British journal of ophthalmology (Br J Ophthalmol) Vol. 105 Issue 11 Pg. 1510-1514 (11 2021) ISSN: 1468-2079 [Electronic] England
• PMID: 32950959 (Publication Type: Journal Article)
• Copyright: © Author(s) (or their employer(s)) 2021. No commercial re-use. See rights and permissions. Published by BMJ.

Chemical References

• Silicones

Topics

• Adult
• Aged
• Aged, 80 and over
• Artificial Lens Implant Migration
• Cataract
• Cataract Extraction (adverse effects)
• Cohort Studies
• Female
• Humans
• Lens Subluxation (etiology, surgery)
• Lenses, Intraocular
• Male
• Middle Aged
• Phacoemulsification (adverse effects)
• Postoperative Complications (epidemiology, etiology)
• Retrospective Studies
• Silicones