Benign transient hyperphosphatasemia in Juvenile Idiopathic Arthritis: a case report.

Abstract

Benign transient hyperphosphatasemia of infancy and early childhood is a self-limiting condition characterized by transiently increased serum alkaline phosphatase in the absence of liver, kidney or metabolic bone diseases. It is often accidentally found in children under five years old and it might be associated with a variety of underlying clinical disorders. Its pathophysiology remains unclear. Herein, we report a case of a 4-year-old girl with a 1-year history of persistent oligoarticular Juvenile Idiopathic Arthritis, who was found to have transient hyperphosphatasemia during a periodic check-up. This clinical case underlines the importance of promptly recognizing this benign condition, which avoids unnecessary extensive investigations.

• Authors: Agna Neto, Manuela Costa, Jaime C Branco, Ana Filipa Mourão
• Journal: Acta reumatologica portuguesa (Acta Reumatol Port) 2019 Oct-Dec Vol. 44 Issue 4 Pg. 317-319 ISSN: 2184-8777 [Electronic] Portugal
• Vernacular Title: Benign transient hyperphosphatasemia in Juvenile Idiopathic Arthritis: a case report.
• PMID: 32281964 (Publication Type: Case Reports, Journal Article)

Chemical References

• Alkaline Phosphatase

Topics

• Alkaline Phosphatase (blood)
• Arthritis, Juvenile (blood, complications)
• Child, Preschool
• Female
• Humans