Abstract | PURPOSE: METHODS: This retrospective, descriptive, observational study included 107 PKPs performed in 96 patients (mean age, 53 ± 12 years). The patients' indications for surgery, best-corrected visual acuity, surface regularity index, surface asymmetry index, topographic astigmatism, central endothelial cell density, central corneal thickness, and graft status were recorded preoperatively, 6 weeks postoperatively, and before (12 ± 2 months) and after (19 ± 4 months) the suture removal. RESULTS: The surgeries included 48 primary PKPs and 59 repeat PKPs. The main indications were corneal ectatic disorders (50%), severe corneal keratitis (21%), and corneal scars (16%) in the primary PKP group and highly irregular astigmatism after PKP (51%) and previous graft decompensation (37%) in the repeat PKP group. From preoperative measurements to the last follow-up visit without sutures, we found significant improvements (P < 0.001 for all) in visual acuity (0.7 ± 0.3 LogMAR to 0.3 ± 0.2 LogMAR), surface regularity index (1.5-1.0), and surface asymmetry index (2.59-1.1). At the last follow-up, the mean outcome measurements did not significantly differ between the primary and repeat PKP groups. Overall, 89 grafts (83%) remained clear at the last follow-up. CONCLUSIONS: In cases of ectatic disorders and highly irregular astigmatism after keratoplasty, 8.5/8.6-mm excimer laser-assisted PKP seems to be an excellent treatment option, achieving a significant improvement in visual acuity.
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Authors | Raul Alfaro Rangel, Nóra Szentmáry, Sabine Lepper, Loay Daas, Achim Langenbucher, Berthold Seitz |
Journal | Cornea
(Cornea)
Vol. 39
Issue 7
Pg. 806-811
(Jul 2020)
ISSN: 1536-4798 [Electronic] United States |
PMID | 32265385
(Publication Type: Journal Article, Observational Study)
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Topics |
- Cornea
(diagnostic imaging, surgery)
- Corneal Diseases
(diagnosis, surgery)
- Corneal Topography
- Female
- Humans
- Keratoplasty, Penetrating
(methods)
- Lasers, Excimer
(therapeutic use)
- Male
- Middle Aged
- Referral and Consultation
- Retrospective Studies
- Treatment Outcome
- Visual Acuity
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