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Silicon nanowire-based therapeutic agents for in vivo tumor near-infrared photothermal ablation.

Abstract
The first example of silicon nanowire (SiNW)-based in vivo tumor phototherapy is presented. Gold nanoparticle (AuNP)-decorated SiNWs are employed as high-performance NIR hyperthermia agents for highly efficacious in vivo tumour ablation. Significantly, the overall survival time of SiNW-treated mice is drastically prolonged, with 100% of mice being alive and tumor-free for over 8 months, which is the longest survival time ever reported for tumor-bearing mice treated with nanomaterial-based NIR hyperthermia agents.
AuthorsYuanyuan Su , Fei Peng , Xiaoyuan Ji , Yimei Lu , Xinpan Wei , Binbin Chu , Chongxi Song , Yanfeng Zhou , Xiangxu Jiang , Yiling Zhong , Shuit-Tong Lee , Yao He
JournalJournal of materials chemistry. B (J Mater Chem B) Vol. 2 Issue 19 Pg. 2892-2898 (May 21 2014) ISSN: 2050-7518 [Electronic] England
PMID32261484 (Publication Type: Journal Article)

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