Abstract | OBJECTIVE: METHODS: We retrospectively analyze 542 adult patients with moyamoya disease admitted to our hospital from 2009 to 2016. In view of inclusion criteria, we divided patients with moyamoya disease into two groups ( hypertension group and non- hypertension group) and summarized their clinical characteristics. Furthermore, we explore the risk factors for unfavorable outcomes in hypertension group. RESULTS: Of 542 adult patients with moyamoya disease, we identified 156 patients (28.8%) with hypertension and 386 patients (71.2%) without hypertension. During follow-up, we hold the views that the prognosis of non- hypertension group was obviously better than hypertension group (P = 0.005) and the complications were prone to occurring to patients with hypertension (P = 0.037). In the multivariate analysis, severe hypertension (OR, 2.746; 95% CI, 1.096-6.822; P = 0.031) and no anti-hypertensive medication (OR, 0.342; 95% CI, 0.131-1.895; P = 0.029) were the independent predictors for postoperative unfavorable outcomes. The common surgical modalities of moyamoya disease (direct and indirect bypass) had no significant difference in future unfavorable outcomes prevention in adult MMD patients with hypertension. CONCLUSIONS:
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Authors | Yonggang Ma, Meng Zhao, Xiaofeng Deng, Dong Zhang, Shuo Wang, Zheng Zeng, Qian Zhang, Jizong Zhao |
Journal | Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
(J Clin Neurosci)
Vol. 75
Pg. 163-167
(May 2020)
ISSN: 1532-2653 [Electronic] Scotland |
PMID | 32249174
(Publication Type: Comparative Study, Journal Article)
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Copyright | Copyright © 2019. Published by Elsevier Ltd. |
Topics |
- Adult
- Cerebral Revascularization
(adverse effects)
- Female
- Humans
- Hypertension
- Male
- Middle Aged
- Moyamoya Disease
(complications, diagnosis, surgery)
- Multivariate Analysis
- Prognosis
- Retrospective Studies
- Risk Factors
- Treatment Outcome
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