Abstract |
The relationship between malaria and malnutrition is complicated, and existence of one may predispose or exacerbate the other. We evaluated the relationship between malaria parasitemia and nutritional status in children living in communities participating in a cluster-randomized trial of biannual azithromycin compared with placebo for prevention of childhood mortality. Data were collected during the low malaria transmission and low food insecurity season. Parasitemia was not associated with weight-for-height Z-score (24 months: P = 0.11 azithromycin communities, P = 0.75 placebo communities), weight-for-age Z-score (24 months: P = 0.83 azithromycin, P = 0.78 placebo), height-for-age Z-score (24 months: P = 0.30 azithromycin, P = 0.87 placebo), or mid-upper arm circumference (24 months: P = 0.12 azithromycin, P = 0.56 placebo). There was no statistically significant evidence of a difference in the relationship in communities receiving azithromycin or placebo. During the low transmission season, there was no evidence that malaria parasitemia and impaired nutritional status co-occur in children.
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Authors | Ahmed M Arzika, Ramatou Maliki, Nameywa Boubacar, Salissou Kane, Catherine A Cook, Elodie Lebas, Ying Lin, Kieran S O'Brien, Ariana Austin, Jeremy D Keenan, Thomas M Lietman, Catherine E Oldenburg, For The Mordor Study Group |
Journal | The American journal of tropical medicine and hygiene
(Am J Trop Med Hyg)
Vol. 103
Issue 3
Pg. 1315-1318
(09 2020)
ISSN: 1476-1645 [Electronic] United States |
PMID | 32067628
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Anti-Bacterial Agents
- Azithromycin
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Topics |
- Anti-Bacterial Agents
(administration & dosage)
- Azithromycin
(administration & dosage)
- Child, Preschool
- Female
- Humans
- Infant
- Malaria
(drug therapy, epidemiology, parasitology, transmission)
- Male
- Mass Drug Administration
- Niger
(epidemiology)
- Nutritional Status
- Parasitemia
(drug therapy, epidemiology, parasitology, transmission)
- Seasons
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