[Effect of Dyes Containing Lutein on Enhanced Visibility of Epiretinal Pathologies in Intraoperative OCT].

Abstract

BACKGROUND:

Epiretinal membranes are a disorder leading to metamorphopsia and loss in visual function. The gold standard in therapy is vitrectomy with membrane peeling, usually performed with chromovitrectomy. The aim of this study was to examine whether dyes containing lutein are capable of enhancing visualization of epiretinal tissue in intraoperative optical coherence tomography (iOCT).

PATIENTS AND METHODS:

This was a prospective study that included 20 eyes of 20 patients with idiopathic epiretinal membranes scheduled for surgery. 23 G pars plana vitrectomy with intraoperative assistance of iOCT was performed in all cases. Staining of epiretinal membranes was performed with dyes containing trypan blue, brilliant blue G and lutein (tripledyne and dualdyne, both Kemin Industries Inc., USA).

RESULTS:

In all patients (n = 20), staining of epiretinal tissue was good, and crystalline lutein particles could be well depicted in iOCT compared to soluble lutein that does not enhance visualisation of epiretinal tissue in iOCT.

CONCLUSIONS:

The addition of lutein to commonly used dye formulations offers good staining properties and, in case of crystalline lutein, also enhances epiretinal tissue in iOCT.

• Authors: Christoph Leisser, Martin Kronschläger, Oliver Findl
• Journal: Klinische Monatsblatter fur Augenheilkunde (Klin Monbl Augenheilkd) Vol. 237 Issue 10 Pg. 1230-1234 (Oct 2020) ISSN: 1439-3999 [Electronic] Germany
• Vernacular Title: Effekt von Chromovitrektomiefarbstoffen mit Lutein auf die verbesserte Darstellung von epiretinalen Pathologien im intraoperativen OCT.
• PMID: 31770788 (Publication Type: Journal Article)
• Copyright: Thieme. All rights reserved.

Chemical References

• Coloring Agents
• Lutein

Topics

• Coloring Agents
• Epiretinal Membrane (surgery)
• Humans
• Lutein
• Prospective Studies
• Tomography, Optical Coherence
• Vitrectomy