Rivaroxaban-induced acute cervical spine epidural hematoma: Report of a case and review.

Abstract

BACKGROUND:

Spontaneous spinal epidural hematomas (SEHs) due to the utilization of factor Xa inhibitors are rare.

CASE DESCRIPTION:

A 66-year-old female presented with a Brown-Sequard syndrome attributed to a cervical epidural hematoma secondary to the utilization of rivaroxaban, one of the factor Xa inhibitors. Following a cervical laminectomy for the evacuation of the hematoma, the patient completely recovered.

CONCLUSION:

A spinal hemorrhagic event should be suspected in patients receiving factor Xa inhibitor drugs. Here, we had an elderly female on rivaroxaban experienced the acute onset of neck/back pain associated with a Brown-Sequard syndrome. A literature review showed that this is the seventh example of SEH occurring as a result of the use of anticoagulation drugs (OACDs; e.g., including Xa inhibitors).

• Authors: Abolfazl Rahimizadeh, Zahed Malekmohammadi, Walter L Williamson, Shaghayegh Rahimizadeh, Mahan Amirzadeh, Naser Asgari
• Journal: Surgical neurology international (Surg Neurol Int) Vol. 10 Pg. 210 ( 2019) ISSN: 2229-5097 [Print] United States
• PMID: 31768290 (Publication Type: Case Reports)
• Copyright: Copyright: © 2019 Surgical Neurology International.