Analysis of social and medical portrait of children with pertussis, meningococcal infectious, scarlet fever and estimation of their assigned pharmacotherapy.

Abstract

OBJECTIVE:

Introduction: The level of childhood bacterial diseases incidence does not have a downward trend. The aim: Conduction of a sociological analysis of medical cards for children with pertussis, meningococcal infection (MI), scarlet fever, and evaluation of consumed pharmacotherapy according to real clinical practice in Ukraine.

PATIENTS AND METHODS:

Materials and methods: 1215 medical cards of inpatients; methods: sociological - document analysis, retrospective frequency.

RESULTS:

Results: Among the cards of children with pertussis: 50.2% - female, 49.8%- male; by age children up to 1 year (49.3%) were prevailed. In 79.6% incidence - medium-hard form pertussis, 42.2% with complications. Among patients with MI by sex there were: 50.5 % - boys and 49.5% - girls; by age - children aged 1-4 (40.2%); the structure of generalized forms of MI: 40.2% - meningococcemia, 11.4% - meningitis, 48.4% - combination. Scarlet fever was more frequently: boys (56.4%), children aged 5-9 (44.7%), urban residents (79.7%); it was 93.4% of a medium-hard form. Most of medicines were prescribed to children with MI - 15.8 trade names per 1 person, it was prescribed 191 INN, most often - Sodium chloride (90.0%), Ascorbic acid (68.5%), Ceftriaxone (65.8%); patients with pertussis - 11.2, 196 INN (Chlorpromazine (69.1%), Dexamethasone (53.2%), Butamirate (51.8%)); scarlet fever - 9.3 medicines, 114 INN (local action Comb drug for throat diseases treatment (94.4%), Ceftriaxone (48.7%), Metamizole sodium (38.1%)).

CONCLUSION:

Conclusions: Frequency analysis data of consumed pharmacotherapy in real pediatric practice in Ukraine shows the need for its further optimization in accordance with the principles of evidence-based medicine, the results of research on the socio-demographic characteristics of patients, forms and complications of course of the basic disease.

• Authors: Oryna Detsyk, Iryna Fedyak, Iryna Bilyk
• Journal: Wiadomosci lekarskie (Warsaw, Poland : 1960) (Wiad Lek) Vol. 72 Issue 9 cz 2 Pg. 1802-1808 ( 2019) ISSN: 0043-5147 [Print] Poland
• PMID: 31622270 (Publication Type: Journal Article)

Topics

• Child
• Child, Preschool
• Female
• Humans
• Incidence
• Infant
• Male
• Meningococcal Infections (drug therapy, epidemiology)
• Retrospective Studies
• Scarlet Fever (drug therapy, epidemiology)
• Ukraine (epidemiology)
• Whooping Cough (drug therapy, epidemiology)