Intravitreal Bevacizumab for Treatment of Bilateral Candida Chorioretinitis Complicated with Choroidal Neovascularization.

Abstract	Purpose: The purpose of this report is to describe a case of bilateral Candida chorioretinitis complicated with choroidal neovascularization (CNV) and effectively treated with combined intravitreal bevacizumab and amphotericin B.Results: An 83-year-old patient was diagnosed with Candida chorioretinitis in both eyes. Optical coherence tomography and fluorescein angiography revealed CNV. Treatment using combined intravitreal bevacizumab and amphotericin B was initiated followed by a 4-weekly regimen of bevacizumab, eventually resulting in the regression of the subretinal fluid and intraretinal edema.Conclusion: Our study supports the combined use of intravitreal bevacizumab and amphotericin B in the management of CNV in Candida chorioretinitis.
Authors	Kirsten E Zonnevylle, Dinu Stanescu-Segall
Journal	Ocular immunology and inflammation (Ocul Immunol Inflamm) Vol. 28 Issue 1 Pg. 39-42 ( 2020) ISSN: 1744-5078 [Electronic] England
PMID	31415218 (Publication Type: Case Reports, Letter)
Chemical References	Angiogenesis Inhibitors Antifungal Agents Coloring Agents VEGFA protein, human Vascular Endothelial Growth Factor A Bevacizumab Amphotericin B Indocyanine Green
Topics	Aged, 80 and over Amphotericin B (therapeutic use) Angiogenesis Inhibitors (therapeutic use) Antifungal Agents (therapeutic use) Bevacizumab (therapeutic use) Candidiasis (drug therapy, microbiology) Chorioretinitis (drug therapy, microbiology) Choroidal Neovascularization (diagnostic imaging, drug therapy, pathology) Coloring Agents (administration & dosage) Drug Therapy, Combination Eye Infections, Fungal (drug therapy, microbiology) Fluorescein Angiography Humans Indocyanine Green (administration & dosage) Intravitreal Injections Male Subretinal Fluid Tomography, Optical Coherence Vascular Endothelial Growth Factor A (antagonists & inhibitors) Visual Acuity (physiology)

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