Multifocal tuberculosis-associated immune reconstitution inflammatory syndrome - a case report of a complicated scenario.

Abstract

BACKGROUND:

Tuberculosis (TB)-associated Immune reconstitution inflammatory syndrome (TB-IRIS) is an aberrant inflammatory response in TB patients with advanced human immunodeficiency virus coinfection, after antiretroviral therapy commencement.

CASE PRESENTATION:

We present a rare case of a 51-year-old woman living with HIV who developed a series of TB-IRIS events occurring at multiple sites sequentially, highlighting the clinical complexity in diagnosis and management.

CONCLUSION:

This case illustrates how complicated a clinical scenario of successive TB-IRIS episodes can be, in terms of clinical management.

• Authors: Gopalan Narendran, Deivide Oliveira-de-Souza, Caian L Vinhaes, Kevan Akrami, Kiyoshi F Fukutani, Kesavamurthy Banu, Padmapriyadarsini Chandrasekaran, Narayanan Ravichandran, Irini Sereti, Soumya Swaminathan, Bruno B Andrade
• Journal: BMC infectious diseases (BMC Infect Dis) Vol. 19 Issue 1 Pg. 529 (Jun 17 2019) ISSN: 1471-2334 [Electronic] England
• PMID: 31208430 (Publication Type: Case Reports, Journal Article)

Chemical References

• Anti-HIV Agents

Topics

• Anti-HIV Agents (adverse effects)
• Coinfection (drug therapy)
• Female
• HIV Infections (complications, drug therapy)
• Humans
• Immune Reconstitution Inflammatory Syndrome (diagnosis, drug therapy, etiology)
• Middle Aged
• Tuberculosis, Pulmonary (complications)