Successful resection of pancreatic metastasis from oesophageal squamous cell carcinoma: a case report and review of the literature.

Abstract

BACKGROUND:

Oesophageal cancer has a high metastatic potential and poor prognosis, with a significant risk of recurrence after radical resection. However, resected pancreatic metastasis from oesophageal cancer is rare.

CASE PRESENTATION:

Eleven years prior, a seventy-year-old woman had been treated with transthoracic radical oesophagectomy for oesophageal squamous cell carcinoma. Four years prior, she had undergone chemotherapy for lymph node recurrence at the splenic hilum and achieved a partial response. She had also received chemoradiotherapy for lymph node recurrence at the splenic hilum 3 years prior; a complete response was achieved. However, routine follow-up with abdominal computed tomography recently revealed a tumour at the pancreatic tail and swollen lymph nodes. The patient underwent distal pancreatectomy on the basis of a pre-operative diagnosis of primary pancreatic cancer, although a histological examination of the surgical specimen revealed metastatic squamous cell carcinoma that was compatible with metachronous pancreatic metastasis from oesophageal squamous cell carcinoma. The patient has been undergoing clinical follow-up without adjuvant therapy and has been disease-free for 24 months after resection of the pancreatic metastasis.

CONCLUSIONS:

Resection of pancreatic metastasis may improve prognosis and should be considered when treating patients with solitary metastasis from oesophageal squamous cell carcinoma.

• Authors: Wataru Koizumi, Minoru Kitago, Masahiro Shinoda, Hiroshi Yagi, Yuta Abe, Go Oshima, Shutaro Hori, Kenta Inomata, Hirofumi Kawakubo, Miho Kawaida, Yuko Kitagawa
• Journal: BMC cancer (BMC Cancer) Vol. 19 Issue 1 Pg. 320 (Apr 05 2019) ISSN: 1471-2407 [Electronic] England
• PMID: 30953505 (Publication Type: Case Reports, Journal Article, Review)

Topics

• Aged, 80 and over
• Chemoradiotherapy, Adjuvant
• Endosonography
• Esophageal Neoplasms (diagnostic imaging, pathology, therapy)
• Esophageal Squamous Cell Carcinoma (diagnostic imaging, secondary, therapy)
• Esophagectomy
• Female
• Humans
• Lymph Node Excision
• Lymph Nodes (diagnostic imaging, pathology, surgery)
• Lymphatic Metastasis (diagnostic imaging, pathology)
• Neoplasm Recurrence, Local (diagnostic imaging, pathology, therapy)
• Pancreas (diagnostic imaging, pathology, surgery)
• Pancreatectomy
• Pancreatic Neoplasms (diagnostic imaging, secondary, therapy)
• Splenectomy
• Tomography, X-Ray Computed
• Treatment Outcome