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Nrf2 activation via Keap1 deletion or sulforaphane treatment reduces Ova-induced sinonasal inflammation.

AuthorsNyall R London Jr, Anuj Tharakan, Michelle Mendiola, Mengfei Chen, Alex Dobzanski, Thomas E Sussan, Michael Zaykaner, Andrew H Han, Andrew P Lane, Venkataramana Sidhaye, Shyam Biswal, Murugappan Ramanathan Jr
JournalAllergy (Allergy) Vol. 74 Issue 9 Pg. 1780-1783 (09 2019) ISSN: 1398-9995 [Electronic] Denmark
PMID30843229 (Publication Type: Letter, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)
Chemical References
  • Allergens
  • Isothiocyanates
  • KEAP1 protein, human
  • Kelch-Like ECH-Associated Protein 1
  • NF-E2-Related Factor 2
  • Sulfoxides
  • Ovalbumin
  • sulforaphane
Topics
  • Allergens (immunology)
  • Animals
  • Disease Models, Animal
  • Disease Susceptibility
  • Humans
  • Isothiocyanates (pharmacology)
  • Kelch-Like ECH-Associated Protein 1 (deficiency)
  • Mice, Transgenic
  • NF-E2-Related Factor 2 (metabolism)
  • Ovalbumin (immunology)
  • Sinusitis (etiology, metabolism, pathology)
  • Sulfoxides

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