Abstract | OBJECTIVES: METHODS: This nested case-control study aimed to determine the incidence of IPA in 405 ICU patients, between July 2012 and June 2014, at 6 hospitals in Jakarta, Indonesia. Phenotypic identifications and galactomannan (GM) tests of sera and lung excreta were performed in mycology laboratory, Parasitology Department, Faculty of Medicine, Universitas Indonesia in Jakarta, Indonesia. RESULTS: The incidence of IPA in the ICUs was 7.7% (31 of 405 patients). A scoring model used for IPA diagnosis showed 4 variables as the most potential risk factors: lung excreta GM index (score 2), solid organ malignancy (score 2), pulmonary tuberculosis (score 2), and systemic corticosteroids (score 1). Patients were included in a high-risk group if their score was greater than 2, and in a low-risk group if their score was less than 2. CONCLUSION: This study provides a novel diagnosis scoring model to predict IPA in ICU patients. Using this model, a more rapid diagnosis and treatment of IPA may be possible. The application of the diagnosis scoring should be preceded by specified pre-requisites.
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Authors | Anna Rozaliyani, Rudyanto Sedono, Anwar Jusuf, Cleopas M Rumende, Wahju Aniwidyaningsih, Erlina Burhan, Prasenohadi Prasenohadi, Diah Handayani, Evy Yunihastuti, Forman E Siagian, Achmad M Jayusman, Adria Rusli, Saleha Sungkar, Joedo Prihartono, Ferry Hagen, Jacques F Meis, Retno Wahyuningsih |
Journal | Saudi medical journal
(Saudi Med J)
Vol. 40
Issue 2
Pg. 140-146
(Feb 2019)
ISSN: 1658-3175 [Electronic] Saudi Arabia |
PMID | 30723858
(Publication Type: Journal Article, Multicenter Study)
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Chemical References |
- Adrenal Cortex Hormones
- Mannans
- galactomannan
- Galactose
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Topics |
- Adrenal Cortex Hormones
(therapeutic use)
- Case-Control Studies
- Galactose
(analogs & derivatives)
- Humans
- Incidence
- Indonesia
(epidemiology)
- Intensive Care Units
(statistics & numerical data)
- Mannans
(metabolism)
- Middle Aged
- Neoplasms
(complications)
- Predictive Value of Tests
- Pulmonary Aspergillosis
(complications, diagnosis, epidemiology)
- Risk Factors
- Tuberculosis, Pulmonary
(complications)
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