A valuable site-directed application in the field of nanomedicine is targeted
drug delivery using magnetic
metal oxide nanoparticles by applying an external magnetic field at the target tissue. The magnetic property of these structures allows controlling the orientation and location of particles by changing the direction of the applied external magnetic field.
Pharmaceutical design and research in the field of nanotechnology offer novel solutions for diagnosis and
therapies. This review summarizes magnetic nanoparticles and magnetic
spinel ferrit's properties, remarkable approaches in magnetic
liposomes, magnetic polymeric nanoparticles, MRI,
hyperthermia and especially magnetic drug delivery systems, which have recently developed in the field of magnetic nanoparticles and their medicinal applications. Here, we discuss
spinel ferrite (SF) as magnetic materials that are a significant class of composite
metal oxides. They contain ferric
ions and have the general structural formula M2+Fe23+O4 (where M = Co,Ni,Zn,etc.). This structure indicates unique multifunctional properties, such as excellent magnetic characteristics, high specific surface area, surface active sites, high chemical stability, tuneable shape and size, and options for functionalization. The review assesses the current efforts on synthesis, properties and medical application of magnetic
spinel ferrites nanoparticles based on
cobalt,
nickel and
zinc. Based on this review, it can be concluded that MNPs and SFNPs have unlimited ability in biomedical applications. However, the practical application of SFNPs on a huge scale still needs to be considered and evaluated.