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Predictors for 30-Day and 90-Day Hospital Readmission Among Patients With Opioid Use Disorder.

AbstractOBJECTIVES:
To identify the incidence, characteristics, and predictors for 30 and 90-day readmission among acutely hospitalized patients with opioid use disorder (OUD).
METHODS:
This retrospective, cohort study evaluated consecutive adults with OUD admitted to an academic medical center over a 5-year period (10/1/11 to 9/30/16). Multivariable logistic regression was used to determine independent predictors for 30 and 90-day readmissions based on pertinent admission, hospital, and discharge variables collected via chart review and found to be different (with a P < 0.10) on univariate analysis.
RESULTS:
Among the 470 adults (mean age 43.1 ± 12.8 years, past heroin use 77.9%; admission opioid agonist therapy use [buprenorphine 22.6%; methadone 27.0%]; medical [vs surgical] admission 75.3%, floor [vs ICU] admission 93.0%, in-hospital mortality 0.9%), 85 (18.2%) and 151 (32.1%) were readmitted within 30 and 90 days, respectively. Among the 90-day readmitted patients, median time to first readmission was 26 days. Buprenorphine use (vs no use) at index hospital admission was independently associated with reduced 30-day (odds ratio [OR] 0.47, 95% confidence interval [CI] 0.24-0.93) and 90-day (OR 0.57, 95% CI 0.34-0.96) readmission; prior heroin (vs prescription opioid) use was associated with reduced 90-day readmission (OR 0.59, 95% CI 0.37-0.94) and length of hospital stay was associated with both greater 30-day (OR 1.02, 95% CI 1.01-1.05) and 90-day (OR 1.04, 95% CI 1.01-1.06) readmission rates.
CONCLUSIONS:
Among patients with OUD taking buprenorphine at the time of hospital admission, 30-day and 90-day hospital readmission was reduced by 53% and 43%, respectively.
AuthorsJessica L Moreno, Sarah E Wakeman, Matthew S Duprey, Russell J Roberts, Jared S Jacobson, John W Devlin
JournalJournal of addiction medicine (J Addict Med) 2019 Jul/Aug Vol. 13 Issue 4 Pg. 306-313 ISSN: 1935-3227 [Electronic] Netherlands
PMID30633044 (Publication Type: Journal Article)
Topics
  • Adult
  • Boston (epidemiology)
  • Female
  • Hospital Mortality
  • Humans
  • Incidence
  • Length of Stay (statistics & numerical data)
  • Logistic Models
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Opioid-Related Disorders (mortality, therapy)
  • Patient Readmission (statistics & numerical data)
  • Retrospective Studies
  • Risk Factors
  • Time Factors

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