Lung transplantation as a viable option of treatment for pulmonary veno-occlusive disease.

Abstract

Pulmonary veno-occlusive disease (PVOD) is a rare form of pulmonary hypertension caused by alteration of pulmonary veins. Many clinical and hemodynamic similarities to idiopathic pulmonary arterial hypertension (IPAH) may cause diagnostic and therapeutic difficulties. This case report is about a patient with PVOD, whose first symptoms of the disease occurred after infectious mononucleosis. Patient was administered with prostacycline (PGI2) mimetic (Treprostinil), what made qualification process and lung transplantation possible. Despite more and more knowledge about causes, ethiopathogenesis and changes in pulmonary veins on molecular level, lung transplantation is the only successful therapeutic option for patients suffering from PVOD.

• Authors: Marek Ochman, Maciej Urlik, Zofia Tatoj, Marta Wajda-Pokrontka, Fryderyk Zawadzki, Magdalena Latos, Marian Zembala
• Journal: Advances in respiratory medicine (Adv Respir Med) Vol. 86 Issue 5 Pg. 249-254 ( 2018) ISSN: 2543-6031 [Electronic] Switzerland
• PMID: 30378654 (Publication Type: Case Reports, Journal Article)

Topics

• Adult
• Humans
• Lung (pathology)
• Lung Transplantation
• Male
• Pulmonary Veno-Occlusive Disease (diagnostic imaging, physiopathology, surgery)
• Respiratory Function Tests
• Tomography, X-Ray Computed
• Treatment Outcome