Efficacy of diclofenac & thiocolchioside gel phonophoresis comparison with ultrasound therapy on acute low back pain; a prospective, double-blind, randomized clinical study.

Abstract

PURPOSE:

To investigate the effect of Phonophoresis (PP) with the combination of nonsteroidal anti-inflammatory drugs (NSAID's) and myorelaxant versus routine Ultrasound (US) treatment with non-therapeutic gel on the patients with acute low back pain (ABP).

METHODS:

Sixty patients with ABP were randomly assigned into 2 groups. In Group 1 (n = 30) US was applied using diclofenac + Thiocolchicoside gel for 10 min and for a total of 10 sessions. In Group 2 (n = 30) the same US protocol was applied with the same setting and timing with Group 1 using US gel that does not contain any pharmaceutical ingredient. Evaluation parameters were Visual numeric scale (VNS), Oswestry Disability Index (ODI), and Shober test.

RESULTS:

Comparison of the results obtained from the two groups before treatment and at second (W2) and sixth weeks (W6) posttreatment showed significant improvement in all parameters in both groups (p < 0.05). Comparison of the groups showed significantly superior improvement in Group 1 for ODI while there was no difference in other parameters at W2. At W6, there was significantly superior improvement in all parameters (p < 0.05) except for Shober test in Group1.

CONCLUSION:

Our results showed that PP treatment is superior than conventional US therapy at short term in ABP patients.

• Authors: L Altan, M Kasapoğlu Aksoy, E Kösegil Öztürk
• Journal: Ultrasonics (Ultrasonics) Vol. 91 Pg. 201-205 (Jan 2019) ISSN: 1874-9968 [Electronic] Netherlands
• PMID: 30139568 (Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial)
• Copyright: Copyright © 2018 Elsevier B.V. All rights reserved.

Chemical References

• Anti-Inflammatory Agents, Non-Steroidal
• Drug Combinations
• Gels
• Diclofenac
• Colchicine
• thiocolchicoside

Topics

• Acute Disease
• Adult
• Anti-Inflammatory Agents, Non-Steroidal (administration & dosage)
• Colchicine (administration & dosage, analogs & derivatives)
• Diclofenac (administration & dosage)
• Double-Blind Method
• Drug Combinations
• Female
• Gels
• Humans
• Low Back Pain (physiopathology, therapy)
• Male
• Middle Aged
• Pain Measurement
• Pain Threshold
• Phonophoresis
• Prospective Studies
• Range of Motion, Articular
• Treatment Outcome
• Ultrasonic Therapy