Effect evaluation on use of bedside fiber bronchoscope in treating stroke-associated pneumonia.

Abstract

Background The bedside fiber bronchoscope has been widely used in the diagnosis and treatment of respiratory disease. This study aims to assess the effect of using bedside fiber bronchoscope in sputum suction and alveolar lavage for treatment of stroke-associated pneumonia (SAP), compared with the use of conventional suction catheter. Methods One hundred and six patients with SAP were randomly divided into control group (n = 53) and experimental group (n = 53) for a controlled study. Patients in the two groups were conventionally treated with phlegm-resolving and anti-infective therapy. The conventional suction catheter was used for sputum suction for patients in the control group, while bedside fiber bronchoscope was used for sputum suction and alveolar lavage in the experimental group. Clinical pulmonary infection score (CPIS) of the two groups was carried out. The heart rate, blood gas, levels of inflammatory factors in serum, and CPIS were contrastively analyzed between the two groups. Results The blood gas (including pH, PaCO2, PaO2) levels of inflammatory factors in serum such as C-reactive protein, procalcitonin, interleukin-6 and tumor necrosis factor, and CPIS (including the third day and seventh day) in the experimental group (n = 53) were all superior to those of the control group (n = 53) (p < 0.05). The results suggested that the pulmonary ventilation condition and inflammatory response of patients with SAP were significantly improved with the use of bedside fiber bronchoscope. Conclusion The use of bedside fiber bronchoscope is beneficial in modifying the pulmonary ventilation and relieving systemic inflammatory response of patients with SAP, exhibiting a great value in clinical application.

• Authors: Qiu Han, Chun Chen, Hai-Qin Hu, Jun Shen, Guang Yang, Bin Chen, Lei Xia
• Journal: Topics in stroke rehabilitation (Top Stroke Rehabil) Vol. 25 Issue 6 Pg. 459-466 (09 2018) ISSN: 1945-5119 [Electronic] England
• PMID: 29785872 (Publication Type: Journal Article)

Chemical References

• Anti-Infective Agents
• Cytokines
• Expectorants
• Procalcitonin
• Ambroxol
• C-Reactive Protein

Topics

• Aged
• Ambroxol (therapeutic use)
• Anti-Infective Agents (therapeutic use)
• Blood Gas Analysis
• Bronchoscopes
• C-Reactive Protein (metabolism)
• Cytokines (blood)
• Expectorants (therapeutic use)
• Female
• Heart Rate (drug effects)
• Humans
• Hydrogen-Ion Concentration
• Male
• Middle Aged
• Pneumonia (etiology)
• Procalcitonin (blood)
• Retrospective Studies
• Stroke (complications)