Investigating the mechanism underlying urinary continence recovery after radical prostatectomy: effectiveness of a longer urethral stump to prevent urinary incontinence.

Abstract

OBJECTIVE:

To assess the chronological changes in urinary incontinence and urethral function before and after radical prostatectomy (RP), and to compare the findings of pelvic magnetic resonance imaging (MRI) before and after RP to evaluate the anatomical changes.

PATIENTS AND METHODS:

In total, 185 patients were evaluated with regard to the position of the distal end of the membranous urethra (DMU) on a mid-sagittal MRI slice and urethral sphincter function using the urethral pressure profilometry. The patients also underwent an abdominal leak point pressure test before RP and at 10 days and 12 months after RP. The results were then compared with the chronological changes in urinary incontinence.

RESULTS:

The MRI results showed that the DMU shifted proximally to an average distance of 4 mm at 10 days after RP and returned to the preoperative position at 12 months after RP. Urethral sphincter function also worsened 10 days after RP, with recovery after 12 months. The residual length of the urethral stump and urinary incontinence were significantly associated with the migration length of the DMU at 10 days after RP. The residual length of the urethral stump was a significant predictor of urinary incontinence after RP.

CONCLUSION:

This is the first study to elucidate that the slight vertical repositioning of the membranous urethra after RP causes chronological changes in urinary incontinence. A long urethral residual stump reduces urinary incontinence after RP.

• Authors: Yoshifumi Kadono, Takahiro Nohara, Shohei Kawaguchi, Renato Naito, Satoko Urata, Kazufumi Nakashima, Masashi Iijima, Kazuyoshi Shigehara, Kouji Izumi, Toshifumi Gabata, Atsushi Mizokami
• Journal: BJU international (BJU Int) Vol. 122 Issue 3 Pg. 456-462 (09 2018) ISSN: 1464-410X [Electronic] England
• PMID: 29489047 (Publication Type: Journal Article)
• Copyright: © 2018 The Authors BJU International © 2018 BJU International Published by John Wiley & Sons Ltd.

Topics

• Aged
• Humans
• Japan
• Magnetic Resonance Imaging (methods)
• Male
• Middle Aged
• Postoperative Complications
• Prospective Studies
• Prostatectomy (adverse effects)
• Prostatic Neoplasms (surgery)
• Recovery of Function (physiology)
• Urethra (diagnostic imaging, physiopathology, surgery)
• Urinary Incontinence (etiology)
• Urinary Tract Physiological Phenomena
• Urodynamics