Controversies in Endoscopic Eradication Therapy for Barrett's Esophagus.

Abstract

Advances in endoscopic eradication therapy for Barrett's Esophagus-associated neoplasia have resulted in a significant paradigm shift in the diagnosis and management of this complex disease. A robust body of literature critically evaluating outcomes of resection and ablative strategies has allowed gastroenterologists to make quality, evidence-based decisions for their patients. Despite this progress, there are still many unanswered questions and challenges that remain. Ultimately, identification of a cost-effective screening modality, biomarkers for risk stratification, and strides to eliminate post surveillance endoscopy after endoscopic eradication therapy are essential to reach our long-term goal for eradication of esophageal adenocarcinoma.

• Authors: Srinadh Komanduri, V Raman Muthusamy, Sachin Wani
• Journal: Gastroenterology (Gastroenterology) Vol. 154 Issue 7 Pg. 1861-1875.e1 (05 2018) ISSN: 1528-0012 [Electronic] United States
• PMID: 29458152 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review)
• Copyright: Copyright © 2018 AGA Institute. Published by Elsevier Inc. All rights reserved.

Topics

• Barrett Esophagus (surgery)
• Catheter Ablation (methods)
• Endoscopic Mucosal Resection (methods)
• Esophagoscopy (methods)
• Humans
• Quality Indicators, Health Care