Influence of angiographic spontaneous coronary reperfusion on long-term prognosis in patients with ST-segment elevation myocardial infarction.

Abstract

OBJECTIVE:

To explore the influence of angiographic spontaneous coronary reperfusion (SR) on the short- and long-term outcomes in patients with ST-segment elevation myocardial infarction (STEMI).

MATERIALS AND METHODS:

Consecutive patients diagnosed as STEMI and undergoing emergent coronary angiography from January 2009 to August 2010 in a single center were enrolled. Patients whose initial coronary blood flow met Thrombolysis in Myocardial Infarction (TIMI) grade 3 were regarded as angiographic SR. Others (TIMI grade < 3) were included into the NSR group and subsequently underwent primary percutaneous coronary intervention (PCI). Patients' characteristics and outcomes were compared.

RESULTS:

A total of 207 patients were eligible for analysis. The coincidence rate of patients both with ≥ 70% ST-segment resolution and ≥ 70% relief of chest pain and SR was 100%. Patients in the SR group (n = 38) were younger, had more smokers, with higher level of platelet count, lower blood glucose and uric acid, and more distal culprit lesions, as compared to the NSR group (n = 169). Importantly, patients in the SR group had lower rates of in-hospital events (0 vs. 22.5%, p < 0.001) with less stents placed (1.03 ± 1.05 vs. 1.59 ± 1.17, p = 0.007). Moreover, there were comparable long-term outcomes (2.6% vs. 6.9%, p = 0.302) between the two groups during 41-month follow ups.

CONCLUSIONS:

Angiographic SR is associated with significantly favorable short-term outcomes.

• Authors: Xiaoming Li, Boyu Li, Jing Gao, Yunfei Wang, Song Xue, Dachuan Jiang, Qi Hua, Jing Li
• Journal: Oncotarget (Oncotarget) Vol. 8 Issue 45 Pg. 79767-79774 (Oct 03 2017) ISSN: 1949-2553 [Electronic] United States
• PMID: 29108357 (Publication Type: Journal Article)