HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

The combined effect of Sango sprout juice and caloric restriction on metabolic disorders and gut microbiota composition in an obesity model.

Abstract
The main purpose of this study was to compare the benefits of SSJ supplementation in obese rats with those achieved only by switching the alimentary regimen from high-fat (HFD) to the regular one (RD) in liver, ileum and prostate. Furthermore, changings in caecal chime microbiota were investigated. SSJ was administered to rats in combination with a RD (HFD-RD + SSJ). The switch from HFD to RD led to a weight loss of almost 9.8 g, and the total cholesterol was found to be significantly lower. In the HFD-RD + SSJ group, all values were improved compared with the HFD control, and the weight decrement was higher (-23.29 g) with respect to HFD-RD. HFD led to a widespread increment of oxidative stress (OS) markers in liver, ileum and prostate. SSJ has shown to improve the results achieved by the suspension of HFD and it has proven effective wherever the only switch in diet regimen failed.
AuthorsFabio Vivarelli, Donatella Canistro, Clara Babot Marquillas, Silvia Cirillo, Gina R De Nicola, Renato Iori, Giacomo Biagi, Carlo Pinna, Fabio Gentilini, Luisa Pozzo, Vincenzo Longo, Moreno Paolini
JournalInternational journal of food sciences and nutrition (Int J Food Sci Nutr) Vol. 69 Issue 2 Pg. 192-204 (Mar 2018) ISSN: 1465-3478 [Electronic] England
PMID28770644 (Publication Type: Journal Article)
Chemical References
  • Biomarkers
Topics
  • Animals
  • Biomarkers (blood, metabolism)
  • Cecum
  • Diet, Healthy
  • Diet, High-Fat (adverse effects)
  • Diet, Reducing
  • Dysbiosis (etiology, immunology, microbiology, prevention & control)
  • Fruit and Vegetable Juices
  • Gastrointestinal Contents (microbiology)
  • Gastrointestinal Microbiome (immunology)
  • Ileum (immunology, metabolism)
  • Liver (enzymology, immunology, metabolism)
  • Male
  • Obesity (diet therapy, metabolism, microbiology, physiopathology)
  • Oxidative Stress
  • Prostate (immunology, metabolism)
  • Protein Carbonylation
  • Random Allocation
  • Raphanus (chemistry)
  • Rats, Sprague-Dawley
  • Seedlings (chemistry)
  • Weight Loss

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: