A new treatment for frostbite sequelae; Botulinum toxin.

Abstract	Frostbite sequelae are a relevant occupational injury outcome for soldiers in arctic environments. A Caucasian male soldier suffered frostbite to both hands during a military winter exercise. He developed sensory-motor disturbances and cold hypersensitivity. Angiography and thermography revealed impaired blood flow while Quantitative Sensory Testing indicated impaired somato-sensory nerve function. Two years after the initial event, he received an off label treatment with Botulinum toxin distributed around the neurovascular bundles of each finger. After treatment, cold sensitivity was reduced while blood flow and somato-sensory nerve function improved. The successful treatment enabled the soldier to successfully pursue his career in the army.
Authors	Arne Johan Norheim, James Mercer, Frauke Musial, Louis de Weerd
Journal	International journal of circumpolar health (Int J Circumpolar Health) Vol. 76 Issue 1 Pg. 1273677 ( 2017) ISSN: 2242-3982 [Electronic] United States
PMID	28452678 (Publication Type: Case Reports, Journal Article)
Chemical References	Botulinum Toxins
Topics	Arctic Regions Botulinum Toxins (administration & dosage, therapeutic use) Frostbite (drug therapy) Hand (blood supply, innervation) Humans Male Military Personnel Norway Young Adult

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