Clinical observation of the efficacy of Bevacizumab combined with argon green laser in treating fundus macular edema.

Abstract

We studied the clinical efficacy of Bevacizumab combined with argon green laser in treating fundus macular edema. From May 2009 to April 2013, 78 patients seeking treatment for macular edema in the First Affiliated Hospital of Nanchang University were enrolled in this study. Patients were randomly divided into two groups: i) The experimental group (n=39) and the control group (n=39). Patients in the experimental group were treated with Bevacizumab (Avastin®) combined with argon green laser, and those in the control group were treated exclusively with argon green laser. Therapeutic effects were compared, and postoperative adverse reactions caused by both treatment methods were compared. Our results showed that, after treatment, the macular foveal thickness was reduced noticeably in both groups, while the therapeutic effect of combined treatment was more prominent. Patients in the experimental group gained the best-corrected visual acuity after one month of treatment, while patients in the control group achieved that after three months of treatment. We concluded that the use of Avastin® combined with argon green laser was safe and effective. Visual acuity was improved obviously with minimum adverse reactions.

• Authors: Yi Shao, Yao Yu, Cheng Li, Chong-Gang Pei, Ping Tu, Yun Han, Gui-Ping Gao
• Journal: Experimental and therapeutic medicine (Exp Ther Med) Vol. 13 Issue 4 Pg. 1480-1484 (Apr 2017) ISSN: 1792-0981 [Print] Greece
• PMID: 28413496 (Publication Type: Journal Article)