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Effect of acidity of in-office bleaching gels on tooth sensitivity and whitening: a two-center double-blind randomized clinical trial.

AbstractOBJECTIVES:
The study aimed to compare the tooth sensitivity (TS) and bleaching efficacy of two hydrogen peroxide gels with different pHs (acid pH [Pola Office, SDI] and the neutral pH [Pola Office+, SDI]) used for in-office bleaching.
MATERIALS AND METHODS:
Fifty-four patients from Brazil and Chile, with right superior incisor darker than A2, were selected for this double-blind, split-mouth randomized trial. Teeth were bleached in two sessions, with 1-week interval. Each session had three applications of 8 min each, according to the manufacturer's instructions. The color changes were evaluated by subjective (Vita Classical and Vita Bleachedguide) and objective (Easy shade spectrophotometer) methods. Participants recorded TS with 0-10 visual analog scale. Color change in shade guide units (SGU) and ΔE was analyzed by Student's t test (α = 0.05). The absolute risk and intensity of TS were evaluated by McNemar's test and Wilcoxon-paired test, respectively (α = 0.05).
RESULTS:
All groups achieved the same level of whitening after 30 days of clinical evaluation. The use of a neutral in-office bleaching gel significantly decreases the absolute risk of TS (28%, 95% CI 18-41) and intensity of TS when compared to the acid bleaching gel (absolute risk of 50%, 95% CI 37-63).
CONCLUSION:
The use of a neutral in-office bleaching agent gel produced the same whitening degree than an acid bleaching gel but with reduced risk and intensity of tooth sensitivity.
CLINICAL SIGNIFICANCE:
Clinicians should opt to use in-office bleaching with a neutral gel than an acid product because the former causes a significant lower risk and intensity of tooth sensitivity.
AuthorsA D Loguercio, F Servat, R Stanislawczuk, A Mena-Serrano, M Rezende, M V Prieto, V Cereño, M F Rojas, K Ortega, E Fernandez, A Reis
JournalClinical oral investigations (Clin Oral Investig) Vol. 21 Issue 9 Pg. 2811-2818 (Dec 2017) ISSN: 1436-3771 [Electronic] Germany
PMID28303471 (Publication Type: Comparative Study, Journal Article, Multicenter Study, Randomized Controlled Trial)
Chemical References
  • Gels
  • Tooth Bleaching Agents
  • Hydrogen Peroxide
Topics
  • Brazil
  • Chile
  • Dentin Sensitivity (chemically induced)
  • Double-Blind Method
  • Female
  • Gels
  • Humans
  • Hydrogen Peroxide (chemistry)
  • Hydrogen-Ion Concentration
  • Male
  • Tooth Bleaching Agents (chemistry)
  • Tooth Discoloration (drug therapy)
  • Treatment Outcome

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