Surgically Induced Necrotizing Scleritis Following Strabismus Surgery Treated Successfully with Topical N-acetylcysteine in a Child with Congenital Fibrosis of Extraocular Muscles and Varadi Papp Syndrome.

Abstract

INTRODUCTION:

Surgically induced necrotizing scleritis (SINS) is a rare but serious disorder that can develop many years after strabismus surgery. It is generally treated with high-dose steroids or immunosuppression.

CASE REPORT:

We describe a patient with Varadi Papp syndrome and congenital fibrosis of the extraocular muscles, who developed surgically induced necrotizing scleritis a month after strabismus surgery and was successfully managed by oral vitamin C and topical N-acetylcysteine 10%.

DISCUSSION:

While SINS is conventionally treated with steroids/immunosuppression, a conservative approach may be tried in milder cases. The role of topical N-acetylcysteine in managing this complication needs to be explored.

• Authors: Muralidhar Rajamani, Vidhya Nagasubramanian, Ahila Ayyavoo, Palany Raghupathy, Ramamurthy Dandapani
• Journal: Strabismus (Strabismus) Vol. 25 Issue 1 Pg. 39-42 (03 2017) ISSN: 1744-5132 [Electronic] England
• PMID: 28140732 (Publication Type: Case Reports, Journal Article)

Chemical References

• Free Radical Scavengers
• Ophthalmic Solutions
• Ascorbic Acid
• Acetylcysteine

Topics

• Acetylcysteine (therapeutic use)
• Administration, Topical
• Ascorbic Acid (administration & dosage)
• Child
• Fibrosis (complications)
• Free Radical Scavengers (therapeutic use)
• Humans
• Male
• Oculomotor Muscles (surgery)
• Ophthalmic Solutions
• Ophthalmologic Surgical Procedures (adverse effects)
• Ophthalmoplegia (complications)
• Orofaciodigital Syndromes (complications)
• Postoperative Complications
• Scleritis (drug therapy, etiology)
• Strabismus (surgery)