[Long-Term Survival of a Patient with Sigmoid Colon Cancer with Multiple Visceral Metastases].

Abstract

A 66-year-old woman underwent total pelvic exenteration for a pelvic tumor. The pathological diagnosis was sigmoid colon cancer T4b(in the small intestine, uterus, and vagina), N0, M0, Stage II . The patient was treated with XELOX for 6 months as adjuvant chemotherapy and was then treated with IRIS for another 6 months. Brain metastasis developed in the left occipital lobe after 12 months, and she underwent craniotomy and enucleation of the tumor. Liver metastasis and peritoneal dissemination metastasis developed 16 months after her initial diagnosis. The patient underwent re-craniotomy and radiotherapy for recurrence of the brain metastasis 18 months after diagnosis and started taking TAS-102 3 months later. She began treatment with CPT-11 plus panitumumab 24 months after diagnosis, and the dose was increased 9 months later(ie, 35 months after the initial diagnosis). The patient remains alive 42 months after surgery.

• Authors: Yoshiyuki Sasaki, Naoto Nishigori, Fumikazu Koyama, Takeshi Ueda, Takashi Inoue, Keijirou Kawasaki, Shinsaku Obara, Takayuki Nakamoto, Yasuyuki Nakamura, Hisao Fujii, Yoshiyuki Nakajima
• Journal: Gan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 43 Issue 12 Pg. 2444-2446 (Nov 2016) ISSN: 0385-0684 [Print] Japan
• PMID: 28133349 (Publication Type: Case Reports, Journal Article)

Topics

• Aged
• Combined Modality Therapy
• Disease Progression
• Female
• Humans
• Neoplasm Metastasis
• Recurrence
• Sigmoid Neoplasms (pathology, therapy)
• Time Factors