Abstract |
Background and study aims The aim of the present study was to determine whether blue- laser imaging (BLI) reduced the miss rate of colon adenomatous lesions compared with conventional white-light imaging (WLI). Patients and methods This was a prospective randomized study of patients undergoing screening and/or surveillance colonoscopy at Saga Medical School, Japan. A total of 127 patients were randomized to tandem colonoscopy with BLI followed by WLI (BLI-WLI group) or WLI followed by WLI (WLI-WLI group). The main outcome measure was the adenoma miss rate. Results The proportion of patients with adenomatous lesions was 62.5 % (40 /64) in the BLI-WLI group and 63.5 % (40 /63) in the WLI-WLI group. The total number of adenomatous lesions detected in the first inspection of the BLI-WLI and WLI-WLI groups was 179 and 108, respectively, compared with 182 and 120 in the second inspection, respectively. The miss rate in the BLI-WLI group was (1.6 %), which was significantly less than that in the WLI-WLI group (10.0 %, P = 0.001). Conclusions Colonoscopy using BLI resulted in a lower colon adenoma miss rate than WLI.Trial registration UMIN 000015677.
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Authors | Ryo Shimoda, Yasuhisa Sakata, Takehiro Fujise, Kohei Yamanouchi, Nanae Tsuruoka, Megumi Hara, Atsushi Nakayama, Daisuke Yamaguchi, Takashi Akutagawa, Kazuma Fujimoto, Ryuichi Iwakiri |
Journal | Endoscopy
(Endoscopy)
Vol. 49
Issue 2
Pg. 186-190
(Feb 2017)
ISSN: 1438-8812 [Electronic] Germany |
PMID | 27842422
(Publication Type: Journal Article, Randomized Controlled Trial)
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Copyright | © Georg Thieme Verlag KG Stuttgart · New York. |
Topics |
- Adenoma
(diagnosis, pathology)
- Aged
- Colonic Polyps
(diagnosis, pathology)
- Colonoscopy
(instrumentation, methods)
- Colorectal Neoplasms
(diagnosis, pathology)
- Diagnostic Errors
(prevention & control)
- Female
- Humans
- Image Enhancement
(instrumentation, methods)
- Lasers
- Light
- Male
- Middle Aged
- Treatment Outcome
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