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The adenoma miss rate of blue-laser imaging vs. white-light imaging during colonoscopy: a randomized tandem trial.

Abstract
Background and study aims The aim of the present study was to determine whether blue-laser imaging (BLI) reduced the miss rate of colon adenomatous lesions compared with conventional white-light imaging (WLI). Patients and methods This was a prospective randomized study of patients undergoing screening and/or surveillance colonoscopy at Saga Medical School, Japan. A total of 127 patients were randomized to tandem colonoscopy with BLI followed by WLI (BLI-WLI group) or WLI followed by WLI (WLI-WLI group). The main outcome measure was the adenoma miss rate. Results The proportion of patients with adenomatous lesions was 62.5 % (40 /64) in the BLI-WLI group and 63.5 % (40 /63) in the WLI-WLI group. The total number of adenomatous lesions detected in the first inspection of the BLI-WLI and WLI-WLI groups was 179 and 108, respectively, compared with 182 and 120 in the second inspection, respectively. The miss rate in the BLI-WLI group was (1.6 %), which was significantly less than that in the WLI-WLI group (10.0 %, P = 0.001). Conclusions Colonoscopy using BLI resulted in a lower colon adenoma miss rate than WLI.Trial registration UMIN 000015677.
AuthorsRyo Shimoda, Yasuhisa Sakata, Takehiro Fujise, Kohei Yamanouchi, Nanae Tsuruoka, Megumi Hara, Atsushi Nakayama, Daisuke Yamaguchi, Takashi Akutagawa, Kazuma Fujimoto, Ryuichi Iwakiri
JournalEndoscopy (Endoscopy) Vol. 49 Issue 2 Pg. 186-190 (Feb 2017) ISSN: 1438-8812 [Electronic] Germany
PMID27842422 (Publication Type: Journal Article, Randomized Controlled Trial)
Copyright© Georg Thieme Verlag KG Stuttgart · New York.
Topics
  • Adenoma (diagnosis, pathology)
  • Aged
  • Colonic Polyps (diagnosis, pathology)
  • Colonoscopy (instrumentation, methods)
  • Colorectal Neoplasms (diagnosis, pathology)
  • Diagnostic Errors (prevention & control)
  • Female
  • Humans
  • Image Enhancement (instrumentation, methods)
  • Lasers
  • Light
  • Male
  • Middle Aged
  • Treatment Outcome

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