Miller Fisher syndrome.

Abstract

A man aged 30 years presented to the emergency department (ED) with ataxia, areflexia, facial weakness, ophthalmoplegia, extremity weakness and back pain for 4 days. 4 days prior to attending the ED, the patient had suffered from diarrhoea for 2 weeks. The diagnosis of Miller Fisher syndrome was performed on the dual basis of clinical features in addition to an investigations report. Nerve conduction studies and anti-GQ1b IgG antibody analysis were requested. Once IgA deficiency was ruled out, the patient was started on intravenous immunoglobulin (400 mg/kg/day).

• Authors: Suresh Kumar Gupta, Kunal Kishor Jha, Mhd Diaa Chalati, Losan Tareq Alashi
• Journal: BMJ case reports (BMJ Case Rep) Vol. 2016 (Oct 13 2016) ISSN: 1757-790X [Electronic] England
• PMID: 27737870 (Publication Type: Case Reports, Journal Article)
• Copyright: 2016 BMJ Publishing Group Ltd.

Chemical References

• Gangliosides
• Immunoglobulin G
• Immunoglobulins, Intravenous
• GQ1b ganglioside

Topics

• Adult
• Gangliosides (immunology)
• Humans
• Immunoglobulin G (blood)
• Immunoglobulins, Intravenous (therapeutic use)
• Male
• Miller Fisher Syndrome (diagnosis, therapy)