Hip structure analysis by DXA of teriparatide treatment: A 24-month follow-up clinical study.

Abstract

OBJECTIVE:

The objective of this study was to perform a hip structure analysis (HSA) of teriparatide (TPTD) treatment in women with postmenopausal osteoporosis.

METHODS:

The study included 96 patients with postmenopausal osteoporosis and received 20 μg TPTD daily. HSA was performed by dual-energy X-ray absorptiometry.

RESULTS:

The percent changes from baseline for the cross-sectional moment of inertia, section modulus, buckling ratio, and femoral strength index based on HSA results were 9.8% (p < 0.01), 10.7%, 3.3%, and 14.9% (p < 0.01), respectively, at 24 months.

CONCLUSION:

Based on the HSA results obtained with DXA, TPTD was effective for hip structures.

• Authors: Takeshi Mochizuki, Koichiro Yano, Katsunori Ikari, Kosei Kawakami, Ryo Hiroshima, Naoko Koenuma, Mina Ishibashi, Toshikatsu Shirahata
• Journal: Journal of orthopaedics (J Orthop) Vol. 13 Issue 4 Pg. 414-8 (Dec 2016) ISSN: 0972-978X [Print] India
• PMID: 27656075 (Publication Type: Journal Article)