[Clinical regularities of myocardial infarction repair].

Abstract

A total of 136 patients with trans- and 200 with non-transmural myocardial infarction (MI) were examined over time for chlorine-soluble mucoprotein (MP), serum hexoses (SH), their fraction-hexoses of glycosaminoglycans (H-GAG), and hexoses of glycoproteins (H-GP), serum, plasma and urine hydroxyproline (SHP, PHP, UHP). The computation of regressions made it possible to prove multidirectional changes in chlorine-soluble MP, SH, H-GAG, SHP, PHP, and in UHP. Approximation of the curves enabled MI patients to be distributed into subgroups marked by rapid and moderate repair tempo. The factors that prolong MI repair according to the X-square test are as follows: age over 60 years, heart aneurysms, recurrent MI, chronic grade 2A heart failure, diabetes mellitus, chronic bronchitis combined with lung emphysema and stage 2 respiratory failure. That whether MI is transmural or non-transmural is not per se the sole factor determining MI repair.

• Authors: B L Movshovich, G A Kaliabin
• Journal: Terapevticheskii arkhiv (Ter Arkh) Vol. 61 Issue 4 Pg. 39-42 ( 1989) ISSN: 0040-3660 [Print] Russia (Federation)
• Vernacular Title: Klinicheskie zakonomernosti reparatsii infarkta miokarda.
• PMID: 2763191 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Glycoproteins
• Hexoses
• Mucoproteins
• Hydroxyproline

Topics

• Glycoproteins (metabolism)
• Hexoses (blood)
• Humans
• Hydroxyproline (blood, urine)
• Mucoproteins (metabolism)
• Myocardial Infarction (metabolism, physiopathology)
• Regeneration
• Regression Analysis