Abstract | OBJECTIVE: METHODS: The clinical data of 18 patients, who were diagnosed as PAD and treated with DCB from October 2013 to June 2014 in Department of Vascular Surgery, People's Liberation Army General Hospital, were retrospectively analyzed.Thirteen male and 5 female patients were in the series, the mean age of the patients was (65±7) years, and the Rutherford's categories were level 3 to 5. Patients were followed up at 3- and 6-month postoperative. The main efficacy end point were late lumen loss(LLL), rate of restenosis and clinically driven target lesion revascularization (TLR). Meanwhile, the clinical events were recorded. RESULTS: Mean lesion length, the percentage of total occlusions and the percentage of in- stent restenosis were (138±91) mm, 9/18 and 2/18, respectively. Rate of technical success was 18/18. At 6-month postoperative, LLL, rate of restenosis and TLR were (0.1±0.9) mm, 2/14 and 0, respectively. There was no deaths or no amputations. CONCLUSION: DCB with paclitaxel is safe in patients with PAD, and associated with reductions in LLL, restenosis and clinically driven TLR 6-month postoperative.
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Authors | Y L Xu, X Jia, W Guo, X P Liu, X Du, G Y Sun, J Zhang, S H Jia, Z Z Hu |
Journal | Zhonghua wai ke za zhi [Chinese journal of surgery]
(Zhonghua Wai Ke Za Zhi)
Vol. 54
Issue 8
Pg. 617-9
(Aug 01 2016)
ISSN: 0529-5815 [Print] China |
PMID | 27502138
(Publication Type: Journal Article)
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Chemical References |
- Cardiovascular Agents
- Coated Materials, Biocompatible
- Paclitaxel
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Topics |
- Aged
- Amputation, Surgical
- Angioplasty, Balloon
(adverse effects, instrumentation, mortality)
- Cardiovascular Agents
(administration & dosage, pharmacokinetics)
- Coated Materials, Biocompatible
- Constriction, Pathologic
- Female
- Femoral Artery
- Humans
- Kaplan-Meier Estimate
- Limb Salvage
- Male
- Middle Aged
- Paclitaxel
(administration & dosage)
- Peripheral Arterial Disease
(diagnosis, mortality, therapy)
- Retrospective Studies
- Time Factors
- Treatment Outcome
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