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Paclitaxel (Taxol)

A cyclodecane isolated from the bark of the Pacific yew tree, TAXUS BREVIFOLIA. It stabilizes MICROTUBULES in their polymerized form leading to cell death.
Also Known As:
Taxol; Anzatax; Paxene; 7-epi-Taxol; Bris Taxol; NSC-125973; Onxol; Paclitaxel, (4 alpha)-Isomer; Praxel; Taxol A; 7 epi Taxol; NSC 125973; NSC125973; Taxol, Bris; Benzenepropanoic acid, beta-(benzoylamino)-alpha-hydroxy-, 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester, (2aR-(2aalpha,4beta,4abeta,6beta,9alpha(alphaR*,betaS*),11alpha,1-2alpha,12aalpha,12balpha))-
Networked: 22016 relevant articles (2928 outcomes, 6555 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1. Stone, Gregg W: 63 articles (01/2017 - 01/2004)
2. Markman, Maurie: 61 articles (11/2020 - 02/2002)
3. Li, Wei: 60 articles (07/2022 - 09/2008)
4. Scambia, Giovanni: 51 articles (10/2021 - 03/2002)
5. Socinski, Mark A: 44 articles (01/2022 - 07/2002)
6. Serruys, Patrick W: 44 articles (10/2019 - 02/2003)
7. Winer, Eric P: 43 articles (05/2022 - 06/2002)
8. Li, Yan: 43 articles (01/2022 - 05/2007)
9. Vergote, Ignace: 38 articles (01/2022 - 03/2003)
10. Wang, Jing: 38 articles (01/2022 - 01/2007)

Related Diseases

1. Neoplasms (Cancer)
2. Breast Neoplasms (Breast Cancer)
3. Ovarian Neoplasms (Ovarian Cancer)
4. Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
5. Stomach Neoplasms (Stomach Cancer)

Related Drugs and Biologics

1. Carboplatin (JM8)
2. Cisplatin (Platino)
3. Paclitaxel (Taxol)
4. Bevacizumab (Avastin)
5. Platinum
6. Gemcitabine
7. Docetaxel (Taxotere)
8. Doxorubicin (Adriamycin)
9. Fluorouracil (Carac)
10. Cyclophosphamide (Cytoxan)

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Therapeutics
3. Combination Drug Therapy (Combination Chemotherapy)
4. Stents
5. Neoadjuvant Therapy