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Overexpression of sirtuin 6 suppresses allergic airway inflammation through deacetylation of GATA3.

AuthorsHyun-Young Jang, Suna Gu, Sang-Myeong Lee, Byung-Hyun Park
JournalThe Journal of allergy and clinical immunology (J Allergy Clin Immunol) Vol. 138 Issue 5 Pg. 1452-1455.e13 (11 2016) ISSN: 1097-6825 [Electronic] United States
PMID27421859 (Publication Type: Letter, Research Support, Non-U.S. Gov't)
Chemical References
  • GATA3 Transcription Factor
  • Gata3 protein, mouse
  • Ovalbumin
  • Sirt6 protein, mouse
  • Sirtuins
Topics
  • Acetylation
  • Animals
  • Asthma (metabolism)
  • GATA3 Transcription Factor (metabolism)
  • Hypersensitivity (metabolism)
  • Inflammation (metabolism)
  • Lung (drug effects, metabolism)
  • Male
  • Mice
  • Mice, Inbred BALB C
  • Ovalbumin (physiology)
  • Sirtuins (metabolism)
  • Th2 Cells (drug effects, metabolism)

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