Repeated fecal microbiota transplantation in a child with ulcerative colitis.

Abstract

We report the case of an 11-year-old girl with ulcerative colitis refractory to conventional therapy, who was subsequently treated successfully with repeated fecal microbiota transplantation (FMT). The patient was steroid dependent despite several infliximab treatments, and colectomy was proposed to improve quality of life. After repeated FMT, she was able to maintain remission with on minimal dose of steroid. Although her fecal microbiota was dysbiotic before FMT, it was restored to a similar pattern as the donor after repeated FMT.

• Authors: Hirotaka Shimizu, Katsuhiro Arai, Jun Abe, Kazuhiko Nakabayashi, Takako Yoshioka, Kenji Hosoi, Makoto Kuroda
• Journal: Pediatrics international : official journal of the Japan Pediatric Society (Pediatr Int) Vol. 58 Issue 8 Pg. 781-5 (Aug 2016) ISSN: 1442-200X [Electronic] Australia
• PMID: 27324973 (Publication Type: Case Reports)
• Copyright: © 2016 Japan Pediatric Society.

Topics

• Child
• Colitis, Ulcerative (diagnosis, microbiology, therapy)
• Colonoscopy
• Fecal Microbiota Transplantation (methods)
• Feces (microbiology)
• Female
• Humans
• Remission Induction