The aim of the present study was to investigate the mid- to long-term clinical performance of
calcium phosphate cement (
CPC) in the treatment of benign bone
tumors in pediatric patients with a follow-up of at least 2-years. The cases of 33 patients with benign bone
tumors treated by
curettage and subsequent implantation of
CPC were retrospectively reviewed. The patients consisted of 13 males and 20 females, with a median age of 13 years and median follow-up time of 79 months. All patients were alive at the time of review. No toxicity was detected in routine blood tests. Radiography was used to confirm that
CPC was well adapted to the surrounding host bone, although the resorbability of
CPC was not obtained for all patients at the final follow-up. Local
tumor recurrence occurred in 4 patients. None of the patients reported post-operative fractures. In total, 6 patients required a second
surgical procedure, as follows: 4 patients in whom local
tumor recurrence occurred; 1 patient with post-operative superficial
wound infection, who underwent
wound debridement; and 1 patient that required the removal of
CPC due to deep
infection at the proximal humerus. All patients had regained full physical function without any
pain at the final follow-up. The present study recommends that the properties of
CPC should be taken into consideration and applied to the reconstruction of bone defects subsequent to
curettage of bone
tumors.