[Treatment of diaper rash with Parfenac lipid ointment (bufexamac). A study by Austrian pediatricians].

Abstract

447 children between 0 and 24 months with diaper dermatitis were treated by topical application of Parfenac-Fettsalbe (Bufexamac). This panel was selected out of 844 patients which were originally in the protocol. The Parfenac-Fettsalbe was well tolerated, 7 children presented local side effects. 62.71% of treated girls showed very good results, whereas 59.89% of boys showed this outcome. Good results were obtained in 24.35% of girls and 21.93% of boys. Very good (no efflorescences remaining) and good results (some remaining efflorescences) were thus found in more than 80% of patients treated: with respect to corticosteroid advoidance this can be regarded as an effective antiphlogistic medication for diaper dermatitis. Non responders might have been superinfected with microorganisms as candida and staphylococci. In addition, epidemiological considerations are reported in that study.

• Authors: G Lubec
• Journal: Padiatrie und Padologie (Padiatr Padol) Vol. 24 Issue 3 Pg. 227-36 ( 1989) ISSN: 0030-9338 [Print] Austria
• Vernacular Title: Behandlung der Windeldermatitis mit Parfenac-Fettsalbe (Bufexamac). Eine Studie Osterreichischer Kinderärzte.
• PMID: 2682472 (Publication Type: Clinical Trial, English Abstract, Journal Article)

Chemical References

• Hydroxamic Acids
• Ointments
• Bufexamac

Topics

• Bufexamac (administration & dosage, adverse effects)
• Clinical Trials as Topic
• Diaper Rash (drug therapy)
• Female
• Humans
• Hydroxamic Acids
• Infant
• Male
• Ointments