[THREE CASES OF DRUG-INDUCED PNEUMONIA CAUSED BY MESALAZINE].

Abstract

We report three cases of drug-induced pneumonia caused by mesalazine. They were all diagnosed as ulcerative colitis and treated with mesalazine orally. Our three cases and literature review revealed that mesalazine-induced pneumonia resemble like eosinophilic pneumonia or organizing pneumonia and that have good prognosis with drug cessation or administration of corticosteroid. The patient of ulcerative colitis is increasing every year and it is anticipated that the patient with mesalazine-induced pneumonia may also increase. In the treatment of ulcerative colitis with mesalazine, we should pay attention with patient's cough or fever for early detection of drug-induced pneumonia.

• Authors: Norimichi Akiyama, Koshi Yokomura, Tsuyoshi Nozue, Takefumi Abe, Takashi Matsui, Takafumi Suda
• Journal: Arerugi = [Allergy] (Arerugi) Vol. 64 Issue 10 Pg. 1334-40 (Dec 2015) ISSN: 0021-4884 [Print] Japan
• PMID: 26727138 (Publication Type: English Abstract, Journal Article)

Chemical References

• Anti-Inflammatory Agents, Non-Steroidal
• Mesalamine

Topics

• Aged, 80 and over
• Anti-Inflammatory Agents, Non-Steroidal (adverse effects)
• Colitis, Ulcerative (drug therapy)
• Female
• Humans
• Male
• Mesalamine (adverse effects)
• Middle Aged
• Pneumonia (chemically induced)
• Young Adult